Abstract

A REVIEW ON EPIDERMODYSPLASIA VERRUCIFORMIS (EV)

D. Lakshman Chaturvedhi*, B. Prasanna Kumar, U. Sai Prasad, K. Chandra Sekhar, A. Rajasekhar, S. K. Abdul Rakeeb and P. Lakshmi Deepak

Abstract

Epidermodysplasia verruciformis (EV), also known as Tree man syndrome, is extremely a rare autosomal recessive hereditary skin disorder. It is associated with high risk of cancer. It is a rare Genodermatosis characterized by a unique susceptibility to cutaneous infection by a group of phylogenetically related human papilloma virus (HPVs). These patients show a defect in cell mediated immunity towards HPVs leads to lifelong disease. The resulting uncontrolled HPV infections result in the growth of scaly macules and papules, with plane warts, pityriasis versicolor like lesions and reddish verrucous plaques mainly on hand and feet.

Keywords: Epidermodysplasia verruciformis, Pityriasis versicolor, Genodermatosis, Verrucous plaques.