Abstract

A STUDY ON IMPACT OF ANEMIA AND PRESCRIBING PATTERNS OF CARDIOVASCULAR MEDICATIONS IN CONGESTIVE HEART FAILURE IN A TERTIARY CARE HOSPITAL, SVIMS

Sathish Kumar Sure, Surendra Pata, Meena Kakarla, Deepika Reddy Basireddygari, Dr. V. Vanajakshamma*, MD, DM, Dr. C. Kapil*, DM, Dr. K. Prasanna Lakshmi, Pharm D. and Dr. V. Jayasankar Reddy M Pharm, PhD,

Abstract

Heart Failure (HF) is a common cardiovascular condition with increasing incidence and prevalence and can result from any disorder that reduces ventricular filling (diastolic dysfunction) and myocardial contractility (systolic dysfunction). Anemia is prevalent in patients with HF but the exact rates vary widely. The main aim was to study the impact of anemia and prescribing patterns of drugs in patients with HF. Objectives are to study the prevalence of anemia in patients with HF, to compare baseline clinical characteristics and outcomes of HF patients with and without anemia and to study the trends in prescribing patterns of cardiovascular medications in HF. It is prospective study and data recorded in patient data collection proforma from the patients of HF during the period of 5 months. The data was analyzed by using Two-sample t-test, Chi-square and One way ANOVA. Our study reveals about 1270 cardiovascular drugs prescribed for 200 patients who are included in the study. Most common class of drugs Prescribed in the treatment were Diuretics (27.56%), Antiplatelets (21.50%), Hypolipidemics (12.05%), Beta Blockers (11.89%), ARBs & ACEIs (9.92%), Cardiac glycosides such as Digoxin (7.17%). The average Hospital stay of severe anemic patients was higher than moderate and mild which was found to be statistically significant. we conclude that polytherapy is better than monotherapy in patients with CHF. Prescription of generic drugs reduces the economic burden of the patients such that making them more affordable and also the chance of survival for long time depends on absence or presence of co-morbidities.

Keywords: Heart failure, ventricular filling, Anemia, polytheapy, monotherapy.