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Abstract

A SIMPLE SPECTROPHOTOMETRIC ASSAY OF EDARAVONE IN BUILK SAMPLES

G. Srihari, U. Sreenivasulu*, K. Prabhavathi and N. Rami Reddy

Abstract

A simple, sensitive, rapid and accurate colorimetric method has been developed for the estimation of edaravone in bulk and pharmaceutical dosage forms. The proposed method was based on the formation of chloroform extractable complex of edaravone with wool fast blue. The absorbance of the extractable ion pair complex is measured at the wavelength of maximum absorbance 585 nm against the reagent blank. Results obtained are statistically validated and found to be reproducible.

Keywords: Spectrophotometry, Wool fast blue, edaravone, Pharmaceutical and Formulation


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