Abstract

PHARMACEUTICAL STANDARDIZATION OF RASAMANIKYA – KUPIPAKVA METHOD

Dipali Parekh*, Sarika Makwana, Dr. B. J. Patgiri and Dr. Prashant Bedarkar

Abstract

Introduction: Rasamanikya is Ayurvedic formulation which is contains heavy metal. It is prepared from single mineral of Shuddha Haratala heating through Kupipakva method. Kushmanda Swarasa has been preferred as media for Shodhana of Haratala. Rasamanikya name itself denotes the drug of Ruby color. Aim: To standardize the pharmaceutical procedure of Rasamanikya by Kupipakva method. Material & Methods: Rasamanikya has been prepared from Kushmanda Swarasa Shodhita Haratala through Kupipakwa method using vertical electric muffle furnace as heating device. Here Rasamanikya is prepared in three batches to establish the standard operating procedure. Results & discussion: Average 0.8 % w/w decreases in weight after Shodhana of Haratala by Kushmanda Swarasa. Average 99.66 % w/w yield was obtained of Rasamanikya prepared with Kupipakva method. Conclusion: In this study average 99.66 % w/w yield is obtained from 1500 g Shuddha Haratala required duration of heating 2 hours. Rasamanikya prepared by Kupipakva method has been taken has standard procedure for large scale preparation.

Keywords: Haratala, Kupipakva rasayan, Rasamanikya, Standardization.