Abstract

A STUDY ON PRESCRIBING PATTERN OF ANTI-MALARIAL DRUGS IN SOUTH INDIAN TEACHING HOSPITAL, KARNATAKA

Shantveer H., Srikanth G.*, Ajay Kumar Yadav B., Tulasi Brundha B. and Siva Krishna CH

Abstract

Background: Malaria is considered as one of most deadliest mosquitoborne disease caused by a single species of parasite Plasmodium with variable genera -P.Vivax, P.Falciparum, P.Ovale, P.Malariae and P.Knowlesi. Malaria istypically known as cyclical infection between Humans and Anopheles mosquitoes which is caused by Plasmodium. Introduction: Malaria is one of most worn out disease which is first reported as a zoonotic disease, of approximately 30 million years old in Palaeogene period. According to World Health Organisation’s World Malaria Report 2017, nearly half the world’s population lives in areas at risk of malaria transmission in 91 countries and territories with most prominent cause of death and incapicitation in vulnerable patients like Children and Pregnant Women. Objectives: The purpose of this study is to assess, analyze and evaluate the pharmacological treatment in the current practise of Anti-Malarial Drugs. Methodology: This study is carried for a period of six months from September 2017 to March 2018 in District Hospital Kalaburagi. A Prospective Observational study has been adopted for the patients data collection and relevant diagnostic reports. However 33 cases were recorded in respective to their diagnostic reports and prescription pattern. Out of which, 23 cases are reported with P.Vivax caused Malaria and 10 cases with P.Falciparum caused Malaria. Results: Findings of our study revealed that P.Vivax caused Malaria (23 cases) is most prevailed parasite in District of Gulbarga when compared with P.Falciparum caused Malaria (10 cases). Our study also revealed that use of solid dosage forms is comparatively highly effective and most commonly prescribed than intravenous forms. Considering the Age, Seasonal variations and Gender bias the severity of disease is moderate to high (Age55years, Seasons - Autumn, Gender- Females). Conclusion: Our study concluded that prescription pattern varies widely based on geograpical location, patient’s characteristics (age and gender) and severity (mild and severe) and seasonal variations. Our study also disclosed the current practise for the treatment of Malaria in South Indian Teaching Hospital and pros and cons in Therapeutic Guidelines followed by acquainting National Drug Policy.

Keywords: Falciparum, Vivax, Ovale, Zoonotic, Plasmodium, Malariae.