Abstract

EVALUATION OF PHYTOCHEMICAL ANALYSIS AND ANTIMICROBIAL ACTIVITY OF PHYLLANTHUS EMBLICA (L.) FRUIT PULP

Ashna C.* and Suganthi A.

Abstract

Phyllanthus emblica (L.) is commonly known as Indian gooseberry. It has been extensively used, both as edible plants and for therapeutic potentials. The fruit of P.emblica have significant medicinal value. It has been used for the treatment of cancer, diabetes, liver treatment, heart trouble, ulcer, anemia and various other diseases. It has application as anti-inflammatory, anti-pyretic and gastroprotective treatments by the rural population. The present study was conducted based on the traditional knowledge of the plant. To evaluate the scientific basis for the use of amla fruit pulp there were study conducted on the isolation of the chemical constituents present in the fruit pulp. The Phytochemical constituents of the dried powdered plant fruits were extracted using chloroform and methanol solvents, results revealed the presence of alkaloids, carbohydrates, glycosides, flavanoids, proteins, amino acids, tannins, phenolic compounds, sterols, steroids, fixed oils, fats and resins. The methanolic extract which have high phytochemical constituents used for the evaluation of antimicrobial activity at 100mg/ml, which evaluated against some common pathogenic bacteria using agar diffusion method. Gram positive bacteria Staphylococcus aureus and gram negative bacteria Pseudomonas aeruginosa were used and antimicrobial activity of the concentrated extracts was evaluated by the diameter zone of inhibition against the above microorganisms. Fruit extract were active against both stains of bacteria. The above observation indicates that P.emblica has broad spectrum antibacterial activity and a potential source of new classes of antibiotics that could be useful for development of new medicines with lesser side effects.

Keywords: Phyllanthus emblica, Methanolic extract, Antibacterial activity, Medicinal value, Traditional knowledge.