Abstract

A REVIEW ON ANALYTICAL METHODS FOR ESTIMATION OF EMTRICITABINE AND TENOFORVIR ALAFENAMIDE FUMARATE IN PHARMACEUTICAL DOSAGE FORM

Kalamkar Chaitali S.* and Dr. Bhawar Sanjay B.

Abstract

This review article is intended to highlight the analytical methods of Emtricitabine and tenoforvir alafenamide fumarate in individual as well as combined pharmaceutical dosage form. Emtricitabine and tenoforvir alafemide fumarate play an important role in HIV infection. Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI) and Tenoforvir alafenamide fumarate is a nucleotide reverse transcriptase inhibitor and a prodrug of tenofovir. Now these days these drugs are easily available in the market in their individual form as well as in their combined dosage form .Various analytical methods have been reported for the estimation of these drugs in their individual form as well as in their combined dosage form.

Keywords: HIV infection, RP-HPLC, Mobile Phase, Column, Wavelength, Flow rate.