Abstract

QUERCETIN AND A REVIEW ON ITS IMPORTANCE

Vikram V. Nimbalkar*, Jyoti M. Hemnani and Ajay B. Shelke

Abstract

Flavonoid quercetin is phytochemical compounds, phenolic in nature &is present in abundance as dietary flavonoid in certain vegetables, grains, fruits, flowers, bark roots, stem, wine and tea.It possess potent antioxidant & anti-inflammatory properties which can be coupled with hepatoprotective and cardioprotective action, in autoimmune disease like Diabetes Mellitus with varying doses. It also has anti-viral, antimalarial property and therefore finds its application as immunomodulatory and thus, can be effective anti-cancer drug. Quercetin as herbal drug has less side effects, but should be used wisely as there are chances of drug-drug interactions or it may also interfere with the drugs that are metabolized in liver by Cytochrome P450 2C8, 2C9, 3A4, 2D6 substrates.

Keywords: Quercetin, Cancer, Phytochemical, Phenolic, Anti-malarial.