Abstract

PLASMINOGEN ACTIVITY AND INHIBITORS IN NORMAL LATE PREGNANCY POSTPARTUM AND IN THE POSTNATAL PERIOD

Taghreed Salah Hadi* and Shurooq Noori Saleh

Abstract

Plasminogen activator activity inhibitors of pregnant women was investigated at various gestation times to assess the availability of plasminogen activator for aiding potential corneal wound healing processes during pregnancy was measured by a spectrophotometric method. The analysis used 91 tear samples from pregnant and nonpregnant women, supplemented with 10 additional inhibitors PAA measurements from non-pregnant women obtained in a previous study in pregnant women formed a bimodal distribution. Either the tear PAA level was zero or non-zero during pregnancy. When non-zero, the tear PAA level was dissociated from gestation time and not different than non-pregnant and postpregnant levels. The frequency of occurrence of zero level tear PAA increased with gestation: 16%, 17%, and 46% had zero tear PAA in samples taken from women in the first, second and third trimester, respectively.

Keywords: Plasminogen activator, postnatal, Postpartum