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WJPR

World Journal of Pharmaceutical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

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Abstract

Î²-CYCLODEXTRIN CATALYSED ONE-POT SYNTHESIS OF ARYL BENZOTHIAZOLES FROM DIMETHYLACETALS IN AQUEOUSPHASE

Ravi Lakkakula, Arnab Roy, Khagga Mukkanti and Mendu Narender*

Abstract

A facile synthetic protocol for 2-arylbenzothiazoles from dimethylacetals and 2-amino thiophenol by using β-cyclodextrin as a mild and efficient catalyst for the formation of inclusion complex in water at 50°C. The reactions using β-cyclodextrin were very fast and proceeds with good yields of the products.

Keywords: Dimethyl acetals, thiophenol, ?-cyclodextrin, supramolecular chemistry.

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