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Abstract

A REVIEW ON METHOD DEVELOPMENT ON ESTIMATION OF ACEBROPHYLLINE AND DOXOFYLLINE

Shinde Madhuri* and H. S. Bhawar

Abstract

Asthama is a common long term inflammatory disease of the airway of the lungs it is characterized by a various reocurring symptoms, reversible air flow obstruction and bronchospasm. Acebrophylline and doxofylline act as anti- asthamatic drug. A simple selective and precise HPLC method of analysis of acebrophylline and doxofylline both in bulk and in their combine formulation has been developed. Various analytical method have been reported for the estimation of these drugs in their individual forms as well as their combined dosage form.

Keywords: Acebrophylline, Doxofylline, RP-HPLC (high performance liquid chromatography), column, mobile phase.


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