Abstract

THE TARGETED DRUG DELIVERY SYSTEM; REVIEW LITERATURE ON NANOTECHNOLOGY, NANO PARTICLES

Sahenur Begam*, Nisha Panda, Sushma Rana, Lotus Behera and Preeti Dehuri

Abstract

Recent advances in the understanding of pharmacokinetic & pharmacodynamic behaviour of drug have offer a more rational approach to the development of optimal drug delivery system. Now it's appreciable that future success in Drug delivery research will largely be result of multidisplinary efforts. If any therapeutic agent that can be the more efficacious and safe using and improved drug delivery system represent both lucrative marketing opportunities for pharmaceutical company and advancement in the treatment of diseases of mindkind. To achieve this goal the correct amount of drug has to be delivered to the site of action along with simultaneous control of the drug input rate. Generally after administration of drug located carrier's through only rate undesired bio distribution of drug molecule systemic administration of drug molecules limitations viz, rapid clearance from the systemic circulation either by metabolism inhibited penetrate target tissues or undesired non- specific uptake by sensitive normal tissue or cell cells.

Keywords: Nanotechnology, NDDS, Alzheimer’s Disease, Pharmacokinetic.