Abstract

A PROSPECTIVE STUDY ON THE MANAGEMENT OF EPILEPTIC DRUGS AND DRUG RELATED PROBLEMS OF EPILEPTIC PATIENTS IN A TERTIARY CARE HOSPITAL

Ashwini*, Sasi Bindhu, Neelima and Nethaji

Abstract

Epilepsy is a chronic neurological disorder characterized by recurrent unprovoked seizures. An epileptic seizure refers to transient occurrence of signs and symptoms due to abnormally excessive or synchronous neuronal activity in the brain. the epileptic seizure may be characterized by sensory, motor or autonomic phenomena with or without loss of consciousness. It has been considered as a public health problem by world health organization (WHO). Worldwide prevalence of the active epilepsy ranges from 4 to 5 per 1000 population. in india, the prevalence rate of epilepsy ranges between 4.15 and 7.03 per 1000 population. Epilepsy adversely affects the psycho-social status and quality of life of patients. Almost any type of brain pathology can cause epilepsy. Our study shows that clobazam and levetiracetem was the anti-epileptic drug preferred in majority of the epilepsy patients. Double therapy of prescribing pattern of antiepilepsy were used for the better control of epilepsy. Management of epilepsy can be achieved through levetiracetem in most of the patients. Around 6% of drug interaction were found and reported to the study department.

Keywords: Clobazam and levetiracetem.