Abstract

SKIN REACTION AT SITE OF INTRATHECAL METHOTREXATE

Ahmed Mjali*, Bushra Najeh Hasan Al Baroodi, Haider Hasan Jaleel Al –Shammari, Rasha K. Muhsin and Nareen Tawfeeq Abbas

Abstract

Complication of intrathecal methotrexate is an issue that is well documented, but development of a dermatological complication like skin burn following administration of intrathecal methotrexate is an extremely rare entity. A 24-year-old female with the diagnosis of acute lymphocytic leukemia (ALL) was put on a treatment regimen, including intrathecal methotrexate. After 2 days following intrathecal methotrexate administration, patient developed burn like skin lesion at site of administration. There was no history of trauma. Intrathecal skin burn may be a very rare, but serious, complication of intrathecal methotrexate administration.

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