Abstract

A COMPARATIVE EXPERIMENTAL STUDY OF GUDUCHI GHANA VATI PREPARED FROM FRESH AND DRY GUDUCHI W.R.T ANTIPYRETIC EFFECT

Vidyashree*, Ashok Kumar B. N., Radhika Ranjan Geethesh P. and
Ravindra Angadi

Abstract

Background and objective: Guduchi ghana vati is widely used in the clinical practice. As per classical reference the drug Guduchi should be always used in fresh form. Most of the pharmacy due to unavailability of fresh Guduchi, using dry Guduchi during preparation of Guduchi ghana vati. Hence the present study was undertaken to evaluate the Antipyretic activity of Guduchi ghana vati prepared from fresh and dry Guduchi in Wistar Albino rats. Methodology: An experimental study was conducted to evaluate antipyretic activity by taking 4 groups with 6 Wistar Albino rats in each group. The results were then analyzed statistically. Results: Fresh Guduchi ghana vati and Dry Guduchi ghana vati group had highly significant antipyretic activity compare to control group. Interpretation and conclusion: Among both the samples dry Guduchi ghana vati group is therapeutically more effective. This may be due to shushka dravyas are guru and tikshna in nature. The reason may be presence of phytoconstituents more in dry Guduchi ghana vati.

Keywords: Guduchi ghana vati, fresh, dry, fever.