Abstract

SOPHISTICATED INSTRUMENTAL ANALYSIS OF POLYHERBAL SIDDHA FORMULATION ASHUWATHI CHOORANAM FOR CURING PCOS

Devaki R.*, Kalpana R., Santhosh Kumar R., Rajamma Devi and Velpandian V.

Abstract

Ashuwathi chooranam (AC) is a polyherbal formulation from the classical Siddha literature. The present investigation was aimed to validate the safety and efficacy of the Siddha poly-herbal formulation AC and standardize the drug by means of physicochemical characters like pH value, ash values, specific gravity, solubility which were analysed. The total ash value was discovered to be 2.64%w/w, water soluble ash value is 1.35%w/w, and acid insoluble ash is 0.185% w/w. The water soluble extractives and alcohol soluble extractives are 46.37%w/w and 46.92%w/w respectively. The pH value is 3.53. The FT-IR spectroscopy in the sample exhibited the presence of functional groups like alkyl halides, aromatics, alkenes, 1º amine, and nitriles. The SEM analysis of the sample displayed that the Nano particles are defined as particulate dispersion or solid particles with a size in the range of 100-800nm in diameter. The XRD analysis of AC concluded in which the major peaks are identified that range 48-75nm in association with organic molecules probably plays an important role in making it biocompatible and nontoxic at therapeutic doses. The ICP-OES analysis in AC revealed the heavy metals such as mercury, lead; cadmium and arsenic are within the limits. The current research is to standardise the AC through modern scientific techniques.

Keywords: Instrument analysis, FT-IR, SEM, XRD, ICP-OES.