Abstract

EVALUATION OF DIURETIC ACTIVITY OF SIDDHA HERBAL FORMULATION DHADHU VIRTHI KULIGAI IN WISTAR RATS

Dr. Rathinam J.*, Dr. Anbarasan B., Dr. Murugavel R., Dr. Harish Anbuselvan V., Dr. M. Murugesan

Abstract

The purpose of the present study was to evaluate the diuretic activity of Dhadhu Virthi Kuligai (DVK) in experimental animals by following the standard procedure. Randomly selected animals were divided into four groups of six animals each. DVK was administered orally at a dose of 100mg/kg b. wt and 200mg/kg b. wt. Parameters like volume of urine, pH of urine and urinary electrolyte concentrations like sodium, potassium and chloride, Lipchitz value and Na+/ K+ ratio were studied. DVK increased the urine output and urinary concentration electrolyte in a dose-dependent manner. There was no significant difference in Lipchitz value and Na+/ K+ ratio. From the present study, it can be concluded that the root of Dhadhu Virthi Kuligai has diuretic property.

Keywords: Dhadhi virthi kuligai, Diuretic, urinary output.