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*Chetana D. Modi1, Dipak Modi2, Ankit Patel1, P.D.Bharadiya3

1Departement of Pharmaceutical Technology, Shree Krishna Institute of Pharmacy, Shankhalpur-384210, Bechraji, Mehsana, Gujarat, India.
2Department of Quality Control, Ratnamani Health care, Indrad. 
3Department of Pharmaceutical Technology, B.S.Patel Pharmacy college, Linch.


Hard gelatin Capsules manufacturing requires large amounts of water removal, requiring great amounts of energy and long drying times. Secondly, these shell materials dissolve slowly when the capsules are being consumed, thereby leaving a distasteful plastic film-like residue in the mouth. Seamless capsules formed of a shell material encapsulating a core material have been made by using as the shell material film-forming materials such as gelatin and gums. Seamless capsules have clear and glossy appearance with liquid material encapsulation and showing greater bioavailability and flexible adjustment of the dosage. Shell of seamless capsules is Heat resistance, Acid resistance & Freezing resistance. Different types of seamless capsules available in the market are described in this review. A variety of materials can be encapsulated in seampless capsules. They are prepared by two methods of manufacturing in use multi component nozzle method and Jet Streams Method/ Drop or Blow Process. Detailed manufacturing method is also described in this review. Seamless capsules are vastly used for Pharmaceutical and Nutraceutical products, Food and confectionary materials & Mouth refreshers, perfumes etc.

Keywords: seamless capsules, Jet Streams Method, Drop or Blow Process, Nutraceutical products.

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