Abstract

A PHARMACOGNOSTICAL AND PHYSICO-CHEMICAL ANALYSIS OF ABHAYADI VATI: AN AYURVEDIC POLYHERBAL FORMULATION

Dr. Sandeep Raman*, Dr. A. B. Thakar, Dr. D. H. Pandya, Dr. Harisha C. R. and Dr. V. J. Shukla

Abstract

In the era of increasing demand for indigenous medicines, maintaining quality standards is the need of the hour. Standardisation of compound formulations is lagging behind because of absence of reference standards. Abhayadi vati is an important Ayurvedic formulation containing Haritaki (Terminalia chebula Retz.), Pippali (Piper longum Linn.), Draksha (Vitis vinifera Linn.), Dhanvyavas (Fegonia cretica Linn.), Sita (Sugar), all the constituents are available and prepared according to the reference present in Yogratnakara Amlapitta nidana chikitsa-35.[1] Hence the present study was undertaken to standardize the compound Ayurvedic formulation through Pharmacognostical and pharmaceutical evaluation. The sample was subjected for various phytochemical parameters like water soluble extractive (48.96%w/w), alcohol soluble extractive (48.03% w/w), ash value (10% w/w), loss on drying (17.82% w/w), the pH (6.5) and hardness (6.5 kg/cm2). The HPTLC, solvent system was Toluene: ethyl acetate (9 :1), showed the presence of 7 spots at 254nm and 2 spots at 366nm. Thus, the physiochemical and microscopic characters achieved may provide guidelines for standardization of formulation Abhayadi vati.

Keywords: HPTLC, Abhayadi vati, Pharmacognostical, Physiochemical Evaluation.