Abstract

PHARMACOGNOSTICAL AND PHARMACEUTICAL EVALUATION OF VAJIGANDHADI YOGA: AN EFFECTIVE FORMULATION FOR THE MANAGEMENT OF CERVICAL SPONDYLOSIS (MANYASTAMBHA)

Appurva Sharma*, Alankruta R. Dave, Harisha C. R. and Shukla V. J.

Abstract

Cervical Spondylosis is a degenerative condition of the cervical spine & common spinal problem seen nowadays. Approximately 95% of people by age 65 have cervical spondylosis to some degree, it’s the most common spine dysfunction in elderly people. Though degeneration of cervical vertebrae is mostly seen in elderly people but due to occupational trauma its prevalence is increasing in early or middle age also. Lots of single and compound drugs have been described in Ayurveda for the management of Vatavyadhi (Manyastambha). Vajigandhadi Yoga is having Rasayana, Balya, Brumhana, and Vatashamaka property. Till date no published data is available on pharmacognostical and analytical profile of Vajigandhadi Yoga, So present study is planned. This paper is made to standardize the formulation through Pharmacognostical and Pharmaceuticals measures. The compound was analysed and standardized scientifically through qualitative and quantitative analysis by physico-chemical parameters and HPTLC and pharmacognostical measures. Pharmacognostical analysis showed characteristics of all the ingredient drugs in the tablet. In Pharmaceuticals analysis, HPTLC was done in appropriate solvent system in which 7 and 3 spots were distinguished at 254 nm and 366 nm respectively. This study may be used as reference standard in the further researches.

Keywords: Cervical Spondylosis (Manyastambha), Pharmaceuticals, Pharmacognostical, Vajigandhadi Yoga.