Abstract

EVALUATION AND PRELIMINARY PHYTOCHEMICAL SCREENING OF HYDROETHANOLIC ROOT EXTRACT OF SOLANUM ANGUIVI LAM. (SYN: S. INDICUM AUCT) FOR ANALGESIC ACTIVITY

Ameena Mehaboob* and Binulal C.

Abstract

The present study focused on the preliminary phytochemical screening and evaluation of analgesic activity of hydroethanolic root extract of Solanum anguivi Lam (Syn: S.indicum auct) belongs to the family Solanaceae. The hydroethanolic extract was prepared by hot continuous extraction (soxhlet). The roots of Solanum anguivi Lam (Syn: S.indicum auct) were collected, dried and powdered. Adult Albino mice of either sex were used for the studies and subdivided into four groups (n=4). The extract was evaluated for analgesic activity using Tail immersion test, Eddy’s hot plate method and Haffner’s tail clip method. The statistical analysis was done through one way ANOVA followed by post hoc Tukey’s multiple comparison tests. The results indicated that the extract depicts statistically significant analgesic activity (P<0.001). Preliminary phytochemical screening of the ethanolic root extract revealed the presence of carbohydrates, saponins, alkaloids, flavonoids, phenols, tannins, steroids & terpenoids.

Keywords: Phytochemical screening, Analgesic activity, Solanum anguivi Lam.