Abstract

EXERCISE-BASED CARDIAC REHABILITATION EFFECTIVENESS IN PATIENTS WITH CORONARY HEART DISEASE: A META-ANALYSIS

Abdulrahman Ali Qasem Al Qasim*, Hatun Fayez Halawani, Slwan Ali O. Alrabaei, Almaha Ali M. Atafi, Adel Mohammad Hakami, Sultanah Hamoud Alruwaili, Seham Matar Alotaibi, Khaled Ali Ali Hakami, Maryam Abdullah Nahas, Mohanad Mohammad Banaamah, Mohammed Awad Mohammed

Abstract

Background & Purpose: Enhancement of exercising capacity via exercising training interventions has, therefore, end up a key thing of the lifestyle and management advice for coronary heart disease patients. The Aim of this work is to provide cumulative data about the effect of exercise-based cardiac rehabilitation in patients with coronary heart disease (CHD). Methods: A systematic search was performed of PubMed, Cochrane library Ovid, Scopus & Google scholar to identify Cardiology RCTs, clinical trials, and comparative studies, which studied the outcome of Exercise group versus Usual care group of CHD patients. A meta-analysis was done using fixed and random-effect methods. The primary outcome was all-cause mortality rate. Secondary outcomes were cardiovascular mortality and hospital admission rates. Results: A total of 6 studies were identified involving 1242 patients, with 622 patients in Exercise group, and 620 patients in Usual care group. Regarding primary outcome measures, the fixed-effects model of the metaanalysis study showed highly significant decrease in all-cause mortality rate in Exercise group compared to Usual care group (p = 0.01). Regarding secondary outcome measures, the fixed-effects model of the meta-analysis study showed significant decrease in cardiovascular mortality rate in Exercise group compared to Usual care group (p= 0.036). The fixed-effects model of the meta-analysis study showed non-significant difference in hospital admission rate in Exercise group compared to Usual care group (p > 0.05). Conclusion: To conclude, in patients with stable CHD, greater physical activity become related to lower mortality. the largest advantages came about among sedentary patient groups and between people with the highest mortality risk.

Keywords: Exercise-based Cardiac Rehabilitation, CHD.