Abstract

PREDICTING THE RISK OF ATROPHIC TRANSFORMATION IN CHRONIC GASTRITIS USING SERUM PEPSINOGEN

Abdullaeva Umida Kurbanovna*

Abstract

The purpose of our study was to research the applicability of measuring serum pepsinogen I (PG I) and PG I / pepsinogen II (PG II) ratios as screening tests for atrophic gastritis, which is the most important predisposition for stomach cancer. Materials and Methods: We measured serum pepsinogen levels in non-specific gastritis, atrophic gastritis and gastric cancer using a radioimmunoassay method. We included in this study 30 healthy control, 30 nonspecific gastritis, 30 atrophic gastritis and 50 gastric cancer cases. Results: The serum PG I level was statistically higher in the control group and in the patient group with chronic nonspecifi c gastritis compared to the patient groups with chronic atrophic gastritis and stomach cancer (p

Keywords: Gastritis, pepsinogen, stomach cancer.