Abstract

NEPHROPROTECTIVE ACTIVITY OF FRESH LEAVES JUICE OF CORIANDRUM SATIVUM AGAINST RENAL ARTERY LIGATION INDUCED NEPHROPATHY

Rama Devi Bhogireddy*, Pushpa Kumari B, Chinnaiah Padarthi, Pitchaiah Dasari,
Dayanand Reddy Gaddam, Ranganayakulu Diviti

Abstract

Aim and objectives: The present was aimed to evaluate the nephroprotective activity of fresh leaves of Coriandrum sativum against renal artery ligation induced nephropathy by taking consideration of kidney parameters in serum as well as urine of experimental animals. Methods: Blood was collected from retro orbital plexus and urine was collected by using metabolic cages. Kidney parameters like creatinine, uric acid, total protein and potassium were measured in both serum and urine of experimental animals. Results: Treatment with fresh leaves juice of C. sativum for 28 days has shown a significant decrease in serum creatinine, BUN and potassium levels and increased levels of serum total protein when compared to control group. Treatment with C. sativum, has shown a significant increase in urinary creatinine, uric acid and potassium levels and significant decrease in urinary total proteins. Conclusion: From the above results we concluded that the fresh leaves juice of C. sativum has good anti-oxidant and renoprotective activities.

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