Abstract

STUDY OF SQUAMOUS CELL CARCINOMAS OF THE LARYNX AND THE REGIONAL LYMPH NODES INVOLVEMENT

Khaled Alhomsi*, Issam Alamine, Ammar Raiy, Hussam Hadid, Imad Alkhuja, Faizeh AL-Quobaili

Abstract

Objective: The purpose of this study is to analyze epidemiological data of patients with laryngeal cancer and to point out the grade of tumors and lymph node metastasis in different stages of the tumors. Materials and Methods: This study is a retrospective cohort study of the records of patients who reviewed AlMouwasat University Hospital and were diagnosed with squamous cell carcinoma (SCC) of the larynx. This study included all records of patients from January 2016 to November 2019. Statistical analysis was done using SPSS 25.0. Results: The males were more predominant than females with a ratio of (4:1). 87% of all patients diagnosed with laryngeal cancer were smokers. Alcohol consumption has been reported in 7% of all patients diagnosed with laryngeal cancer. 45% of all cancers were in the glottis, while 51% were found in the supraglottic region and 4% were in the subglottic region. Most of the patients regardless of the location of the tumor had an advanced staging. Lymph node metastasis was found in 39% of glottic tumors, in 56% of the supraglottic tumors and in 83% of subglottic tumors. Conclusion: Most of the patients had an advanced staging of the tumors. Lymph node metastasis was most common in subglottic tumors followed by supraglottic tumors then glottic tumors, which were the least common.

Keywords: Malignant Laryngeal Tumors, Lymph node metastasis, Syrian Population, AlMouwasat University Hospital.