Abstract

QUANTUM CHEMICAL ANALYSIS OF THE INTERACTIONS BETWEEN INOSITOL AND THE 20 ESSENTIAL AMINO ACIDS

*Petrone-Loyo Giovanna, García-Pérez Vanessa, Martínez-Velasco Vania, Tellez-Quijano Andrea and **González-Pérez Manuel

Abstract

In recent years, many researchers have studied the effect of Inositol and some of its derivatives. These studies have been done on cancer cells and other diseases. The results indicate that there are no significant effects on mitochondrial metabolic activity. In this way, it is known that the total protein profile does not show an alteration with the treatment of Inositol and some derivatives. The objective of this research work was to analyze the chemical-quantum interactions between Inositol and the 20 essential Amino Acids (AAs) using the ETC theory of quantum chemistry. The Hyperchem quantum simulator was used to calculate the quantum variables corresponding to the theory. The calculations were grouped into two main areas: a) Pure substances, b) Cross bands. The results indicate that the Inositol is safe for ingestion in humans. There are only two dangerous interactions, Arg: Inositol and His: Inositol. In these two interactions, Inositol oxidizes these two AAs with a medium probability. We conclude that Inositol is a safe drug for feeding patients. We recommend that it be administered in appropriate doses. High doses could severely affect the patient by their side reactions with the two AAs Arg and His.

Keywords: Inositol, amino acids, quantum chemistry. Arginine, Histidine.