SIMULTANEOUS SPECTROPHOTOMETRIC DETERMINATION OF PIOGLITAZONE AND GLIMEPIRIDE IN BULK AND PHARMACEUTICAL DOSAGE FORM BY USING ABSORBANCE RATIO METHOD
Tejaswini Kande*, Pallavi Dhekale, Supriya Khatal and Priyanka Borude
Abstract
Glimepiride and Pioglitazone in combination are available as tablet
dosage forms in the ratio of 2: 15. A simple, reproducible and efficient
spectrophotometric method has been developed for the simultaneous
estimation of Glimepiride and Pioglitazone in bulk and tablet dosage
forms. The sampling wavelengths selected are 227 nm and 235 nm,
Absorption Ratio Method, the sampling wavelengths selected are 251
nm (iso-absorptivity wavelength) and 235 nm.
Keywords: Pioglitazone, Glimepiride, UV-Visible Spectrophotometric, Validation.
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