Abstract

UV-SPECTROCTOPHOTOMETRIC ESTIMATION OF PARACETAMOL IN DIFFERENT MARKETED BRANDS OF PARACETAMOL TABLET IN SOLID DOSAGE FORM

Amol Giri*, Devanand Dongre and Prafulla Tathe

Abstract

In Present study, Estimation of Paracetamol content in different three marketed brand of Paracetamol Tablet formulation from different manufacturer. Quantitative estimation of Paracetamol carried out by UV visible Spectrophotometric method by single point standardization and calibration plot method. Single point standardization percentage of paracetamol present below the label claimed limit and same tablet formulation estimated for percentage purity test using calibration plot method observed quantity of paracetamol is below the labeled contain. The marketed product of paracetamol might be less amount of paracetamol present therapeutic effect of formulation depends on its quality of product.

Keywords: UV Spectrophotometer, Paracetamol tablet, Single point standardization, Calibration plot method.