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WJPR

World Journal of Pharmaceutical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

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Abstract

MONTMORILLONITE: A MILD AND EFFICIENT RECYCLABLE SOLID ACID CATALYST FOR DETRITYLATION OF TRITYL TETRAZOLE IN SARTAN MOLECULES

D. Raju, G. Prabhakar, *B. Madhavarao, K. Sudhakar, M. Rajesh, B. M. Choudary

Abstract

Proton and metal ion-exchanged Montmorillonite catalyzes the detritylation of trityl tetrazole in sartan molecules under mild conditions in high yields. The reactions are carried out in methanol in presence of 1 equivalents of water. Catalyst was reusable without any appreciable loss in its catalytic activity.

Keywords: detritylation montmorillonite sartan molecules.

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