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Abstract

FORMULATION AND EVALUATION OF FAST DISSOLVING UNCOATED TABLETS OF DROTAVERINE HCL

Deovrat Kumar*, Amit Kumar, Jitender K. Malik and Dr. Pooja Semwal

Abstract

In the present work, fast dissolving tablets of drotaverine HCl were prepared by direct compression method with a view to enhance patient compliance The aim of the present research work was to formulate drotaverine HCl tablets using Ac-Di-Sol Superdisintigrant, which is already used as antispasmodic drug. It was selected to enhance solubility and consequently bioavailability of Drotaverine HCl, by determining the Quality assurance parameters during manufacturing, which influence the dissolution behavior of the drug hence its bioavailability.

Keywords: Fast dissolving tablets, drotaverine HCl & Ac-Di-Sol Superdisintigrant.


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