FORMULATION AND EVALUATION OF FAST DISSOLVING UNCOATED TABLETS OF DROTAVERINE HCL
Deovrat Kumar*, Amit Kumar, Jitender K. Malik and Dr. Pooja Semwal
Abstract
In the present work, fast dissolving tablets of drotaverine HCl were
prepared by direct compression method with a view to enhance patient
compliance The aim of the present research work was to formulate
drotaverine HCl tablets using Ac-Di-Sol Superdisintigrant, which is
already used as antispasmodic drug. It was selected to enhance
solubility and consequently bioavailability of Drotaverine HCl, by
determining the Quality assurance parameters during manufacturing,
which influence the dissolution behavior of the drug hence its
bioavailability.
Keywords: Fast dissolving tablets, drotaverine HCl & Ac-Di-Sol Superdisintigrant.
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