Abstract

ENZYME ACTIVITIES OF AKP, CPK, SGOT & LDH IN BLOOD SERUM OF MALARIA PATIENTS

Purohit Chitra*, Jain Suman

Abstract

Malaria is one of the most serious tropical diseases in the world. It becomes a severe health problem in country like India due to poor hygienic conditions; malnutrition borne non-defensive immunity system. Enzyme activity plays vital roles in metabolic pathways & are disturbed in malarial patients. In present study, blood serum Creatine phosphokinase (CPK), Lactate Dehydrogenase (LDH), Alkaline Phosphatase (AKP) & Glutamate Oxalo-transaminase (SGOT) activity was evaluated in 30 malarial patients & in the same number of normal control subjects using kit method. The enzyme activity of AKP, LDH & SGOT increases significantly, whereas the activity of CPK decreases in malarial patients as compared to control subjects.

Keywords: malaria, creatine phosphokinase, lactate dehydrogenase, Liver enzymes, alkaline phosphatase.