Abstract

A REVIEW: NANOPARTICLES USED IN ANTICANCER THERAPY

Nurjahan B. Mulla* and Dr. Sachin A. Nitave

Abstract

Nanotechnology is the study and use of structures between 1 nanometer and 100 nanometers in size. Cancer is the leading cause of death among most of people. Nanoparticles that deliver chemotherapy drugs directly to cancer cells. Nanomedicine application areas include drug delivery, therapy, diagnostic, imaging and antimicrobial techniques. This article aims at giving an overview of the present use of nanotechnology in cancer therapy. Conventional treatment methods, such as chemotherapy or radiotherapy, suffer from a lack of specific targeting and consequent off-target effects. Therefore there is need of development of smart nanosystems which can effect specific regional and temporal activation. In this review, we will discuss the synthesis of different nanoparticles, principle of nanotechnologies in cancer treatment. These can be divided into mechanisms which take advantage of the differences between healthy cells and cancer cells to trigger activation, and those which activate by a mechanism extrinsic to the cell or tumour environment.

Keywords: Nanotechnology, Nanoparticles, Synthesis of nanoparticles, Nanoparticles for cancer, Advancement of Nanotechnology.