Abstract

GREEN SYNTHESIS OF SILVER NANOPARTICLES OFRICINUS COMMUNIS AND INVESTIGATION OF IN-VITRO ANTHELMINTIC ACTIVITY AGAINST PHERETIMA POSTHUMA

Babar A. S., Sankpal P. S., *Bhusnar S. S. Chhalwadi A. S. and Divtankar A. B.

Abstract

Development of anthelmintic drugs leads to evaluation of medicinal plants as a source of anthelmintic. In view of this, an attempt has been made to study the anthelmintic activity of leaves of plant of ricinus communis silver nanoparticles. In the current study, experiments were conducted to evaluate the possible anthelmintic activity of silver nanoparticles of the leaves of plant extract of ricinus communis. Various concentrations (10, 20, 30, 40, 50 μg/ml) of nanoparticles were tested and results were expressed in terms of time for paralysis and time for death of worms. Albendazole used as a reference standard and saline as a control group. The prepared nanoparticles showed particle size with mean diameters 328.4 nm and zeta potential -19.6 mV.

Keywords: Ricinus communis, Anthelmintic activity.