Abstract

SYNTHESIS AND ANTIBACTERIAL ACTIVITY STUDIES OF 8, 9- DI HYDRO- 7H - BENZO - N-(BENZYLOXY)-2-(4-METHYL-COUMARIN- 4/6-YLOXY)-ACETAMIDES AND ITS DERIVATIVES

Niranjan Kolichala, T. Bhupalreddy and Vasantha Kumar Pai*

Abstract

Synthesis, spectral analysis and bioactivity of new coumarin derivatives are described in this paper. Twele new coumarin derivatives were synthesized in moderate to good yields by coupled with hydroxyl amines via acid chloride method. The structures of all the newly synthesized molecules were assigned by elemental analysis and spectral data. The synthesized compounds were screened for their antibacterial activities strains using Cup plate method.

Keywords: Antibacterial activity, hydroxyl amines, benzyl halides.