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Abstract

SPECTROPHOTOMETRIC DETERMINATION OF HALOPERIDOL IN PHARMACEUTICAL FORMULATIONS

D. Venkateswarlu*, G. Sreedevi, I. E. Chakravarthy and N. Rami Reddy

Abstract

A simple, sensitive, rapid and accurate colorimetric method has been developed for the estimation of haloperidol in pharmaceutical formulations. The proposed method was based on the formation of chloroform extractable complex of haloperidol with phenol red. The absorbance of the extractable ion pair complex is measured at the wavelength of maximum absorbance 485 nm against the reagent blank. Results obtained are statistically validated and found to be reproducible.

Keywords: Spectrophotometry, phenol red, haloperidol, Pharmaceutical and Formulation.


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