Abstract

FORMULATION AND EVALUATION OF FAST DISSOLVING TABLETS OF CHARANTIN USING TWO DIFFERENT TECHNUQUES

H. M. Meghana* and J. Adlin Jino Nesalin

Abstract

Fast dissolving tablets considered as an innovative dosage form to avoid the problem of swallowing and to provide quick onset of action. Here Charantin containing fast dissolving tablets were prepared by using two different techniques i.e., direct compression and sublimation method. All the formulations in both methods prepared by using three different superdisintegrants viz Crospovidone, Croscarmellose sodium and sodium starch glycolate in 5% and 10% concentration. And in sublimation technique Camphor used as sublimating agent. Then all the prepared formulation was evaluated for certain pre formulation parameters and also post formulation parameters. Comparative study of two different methods shows that sublimation method is a better alternative to direct compression technique.

Keywords: Charantin, Crospovidone, Croscarmellose sodium, Sodium starch glycolate, Direct compression method, Sublimation method.