Abstract

A STUDY OF RELATIONSHIP BETWEEN SERUM T3, T4 AND TSH WITH LIVER ENZYMES AST, ALT AND ALP IN PATIENTS OF CHRONIC LIVER DISEASES

Vivek Chourasiya, Dr. Sapneh Sharma, Dr. Arun Mishra* and Dr. Himani Muniyal

Abstract

Objective: The present study is aimed to show the relationship between serum level of markers of thyroid function and chronic liver disease (CLD). Materials and Methods: This study was conducted on 80 subjects attending index medical college and Hospital. Statistical analysis was done using SPSS 20.0. Results: The mean value of activity of AST, ALT and ALP enzymes was significantly higher compared to healthy controls whereas the serum values of T3, T4 and TSH was found to be low in CLD patients. Conclusion: In this study we assessed that the levels of T3 and T4 in CLD patients were significantly decreased to healthy controls. Although the values varied still there was no significant cause effective relationship observed. Therefore, this study confirms the existence of several abnormalities in thyroid function test in CLD.

Keywords: AST, ALT and ALP.