Abstract

NANO FORMUATIONS: PREPARATIONS AND STABILITY CHALLENGES

Habeeba T. U., Nishad K. M.*, Sirajudheen M. K. and Shiji Kumar P. S.

Abstract

Nano drug delivery system is engineered technologies that use nanoparticle size ranges from 1-100nm to the target drug delivery by controlled release of therapeutic agent. This modern form of a drug delivery system reduce both dosage and dosage frequency. Novel drug delivery system is that it is ahead of conventional dossage forms, it bring forth optimum dose at the right time and right location, well regulated use of exorbitant drugs and excipients, depletion on production cost, advantages to patients, superior therapy. Nanoformulations are formulations of nano medicine. The nano medicine compass nanoparticles for the treatment and diagnosis of disease in more efficacious way. The drug is loaded on the nano carrier which are used for the dispatch of drug to the target tissue meticulous or controlled manner. Disparate nanocarriers used in drug delivery system are liposomes, solid lipid nanoparticles, carbon nanotube, virus based etc. Application of these particle provide expeditious and intense development in the field of medicine, health and technology. Nano formulations in target drug delivery used to treat cardio-vascular disease, diabetics and cancerous tumours. Many challenges observed are protein Corona, toxicity, stability etc. These challenges should be solved to enhance the potential and make more effective in physical, chemical, and therapeutic formulations.

Keywords: Organic and inorganic nano carriers, preparations and challenges.