Abstract

ANALGESIC AND ANTIEMETIC ACTIVITIES OF FICUS EXASPERATA VAHL., AND CLEOME CILIATA SCHMACH AND THONN.

Misbah Zubair, Syed Waseemuddin Ahmed, Salman Ahmed*, M.Shaiq Ali andPatrricia Akpomedaye Onocha

Abstract

The present investigation is an attempt to evaluate analgesic and antiemetic activities of Ficus exasperata; Cleome ciliata leaves methanolic extract by using chick emesis model (oral treatment) and acetic acid induced writhing test (intraperitoneal treatment) in mice respectively. The antiemetic activity (150 mg/kg b.w., of extract) was carried out by using chlorpromazine (150mg/kg) as standard antiemetic drug. The analgesic activity (250 mg/kg b.w., of extract) was performed by using aspirin (150mg/kg) as standard analgesic drug. The results showed significant analgesic and antiemetic effects.

Keywords: Ficus exasperata; Cleome ciliata; antiemetic; analgesic; chick emesis model; acetic acid induced writhing test.