Abstract

ENCEPHALITIS: COMPLETE BRIEF REVIEW

Asheesh Kr. Mishra*, Shehreyar Khan, Pankaj Gautam and Sujeet Kumar

Abstract

ENCEPHALITIES represents the inflammation of brain parenchyma typically, symptoms of encephalitis occurs including personality change, fever, seizures, consciousness, neurological shortage, and coma. All patients with suspected encephalitis should undergoes blood cultures and HIV testing. Acute viral encephalitis is direct infection of neural cells with perivascular inflammation, neural destruction, and neuronophagia and tissue necrosis. This consider non-viral diseases, which may necessitate urgent treatment and well detect cases due to HSV. Limbic include HSV cause inflammation in the CNS including limbic area of the brain. The etiology remain unknown, despite extensive diagnostic evaluation. The epidemiology of various causes of encephalitis has changed in recent years in the United States and commonly identified HSV, WNV, and Enterovirus. Symptoms include confusion, agitation, seizures, muscle weakness and double vision, and in infants and young children may also include nausea and vomiting, body stiffness, inconsolable crying, poor feeding, irritability. It diagnosed with different ways such as ELISA, CT, MRI, EEG, CSF, and serological testing. Treatment is carried mostly by cases series and experts consensus, which suggest first line therapy with i.v. IgB, high dose corticosteroid, plasmapheresis, or a combination. Used drugs are (acyclovir, ganciclovir, foscarnet). Therapy may be given if required depend on patients conditions.

Keywords: Inflammation, herpes simplex virus (HSV), brain parenchyma.