Abstract

SYNTHESIS AND ANTI OXIDANT ACTIVITY OF 2-OXO-7- PHENOXY-2H-CHROMENE-3-CARBONYL CHLORIDE

Dr. P. R. Logesh Kumar*, S. Prasanna, V. B. Libitha, E. Santhosh Kumar, Dinakar Bhavana and P. Abdul Rasheed

Abstract

Coumarin (2H-1-benzopyran-2 one) is a plant derivative natural product. Coumarin is important class are the important class of heterocyclic compound possessing interesting biological and pharmacological properties as anticoagulant, antifungal. Anti-viral, Anticancer. Anti-tubercular. Anti- oxidant and neuroprotective properties Coumarin consist of a large class of phenolic substance found in plant and are made of fused benzene and α-pyrone rings. More than 1300 coumarins have been identified as secondary metabolites from plants. Bacteria and fungi. the prototypical compound is known as 1.2. benzopyrone. However, the most of the pharmacological and biological studies have been done on coumarin itself and biochemical studies have been done on coumarin itself and on its primary metabolite. 7-hydroxy coumarin in man.

Keywords: Coumarin. Anti-coagulant. Benzene. Neuro protective property.