Abstract

A REVIEW ON “DEVELOPMENT AND EVALUATION OF LIPOSOMES

*Rachna Tonger, Dr. Hariom Sharma and Monika Setia

Abstract

Liposomes are simple microscopic vesicles in which an aqueous volume is entirely enclosed by a membrane compose of a lipid moiety and are well known to alter the bio-distribution of entrapped substances by protecting the enclosed materials. They are widely used as vehicles or carriers to target the specific molecule to a specific organ especially in condition of bacterial infections. Development of system which controls the release and enhances the bioavailability of chemical agents. This study aimed at developing and optimizing liposomal formulation for maximum therapeutic efficacy with minimal side effects by lipid film hydration technique using various ratios of soya lecithin and cholesterol.

Keywords: Cholesterol and Soya lecithin, Phosphate buffer, Stearic acid acetone ethanol.