Abstract

A REVIEW ON SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL INVESTIGATION OF SOME NOVEL PHENOTHIAZINE DERIVATIVE

Shamal S. Gaikwad*, Nachiket S. Dighe and Sagar D. Magar

Abstract

The aim of this review article is given to a systemic approach on synthetic and different biological activities related with the phenothiazine derivative. From last few decades a considerable amount of attention has been focused on synthesis of phenothiazine derivative and screening them for various biological activities. Phenothiazine effective in various type of biological activity such as antidrepssant, antimicrobial, anticonvulsant, ant psychotropic, Antitubercular activity, antiparasitic, and antiviral. it possess antiviral activity against chikungunya viruses (CHIKV). Phenothiazine derivative associate better activity than standard drug. Thiazolidine and Oxazolidine contain basic skeleton of phenothiazine.

Keywords: Thiazolidine, Oxazolidine, antidepressant, anticonvulsant, antimicrobial, Antitubercular.