Abstract

AN ADVANCE REVIEW ON SALICYLIC ACID OINTMENT FOR TREATMENT OF ACNE

Aditi Kotiyal*, Yogita Tyagi, N. G. Raghavendra Rao

Abstract

Main objective of this study was to formulate the ointment with different ointment bases for topical delivery of water insoluble anti acne agent salicylic acid to enhance the solubility penetration through skin for its activity. The medicated ointment was prepared by using incorporation method in which the active drug has been incorporated in ointment base for topical delivery via skin. To assess the efficacy of the formulation assay, drug release, diffusivity, viscosity, rheology, spreadability, permeability and other physical characterstics were evaluated. Topical ointments provides a suitable delivery system for drug which are water insoluble and having low solubility or having poor penetration efficiency. This review focuses on research till now done on anti acne ointment an detailed study over it.

Keywords: Anti acne ointment, Salicylic acid, Solubility, Penetration.