Abstract

ASSESSMENT OF HYPOGLYSEMIC ACTIVITY OF ETHANOLIC EXTRACT OF PIPER LONGUM LEAVES IN RATS

Achla Vyas* and Kapil Vyas

Abstract

Diabetes Mellitus is a worldwide epidemic. The dominance of the disease is predicted to smash around three hundred million in the year 2018 which is equivalent to near about 8.7% of the world people. The available drugs for diabetes, Insulin or oral hypoglycaemic agents have one or more side effects. Search for new antidiabetic drugs with minimal or no side effects from medicinal plants is a challenge according to WHO recommendations. In this aspect, the present study was carried out with interest to found out a new organic molecule which has potent to cure diabetes, produce less toxic effect. Piper Longum leaves were collected and its ethanolic extract has been extracted out. This ethanolic extract has been analysed for phyto -chemical screening, and then Hypoglycaemic activity of this extract has been evaluated by examine it on Rats. The obtained results shows Piper Longum extract was found to have marked antidiabetic activity adjacent to Alloxan provoke diabetes.

Keywords: Hyperglycaemic, Diabetes Mellitus, Piper Longum, phytochemical screening, Acute study.