Abstract

PHARMACOGNOSTICAL AND PHARMACEUTICAL ANALYSIS OF TRIPHALADI COMPOUND –AN AYURVEDIC POLYHERBAL FORMULATION FOR SHUSHKAKSHIPAKA (DRY EYE)

Vidya N. V.*, Bineesh E. P. and Dr. D. B. Vaghela

Abstract

Background: Dry eye syndrome is a common multy factorial problem with increasing worldwide prevalence, producing symptoms of discomfort, visual disturbances and tear film instability[1], Shushkakshipaka an etymologically and clinically similar entity to DES (Dry Eye Syndrome) is a sarvagata netra roga[2] i.e. the disease affecting all parts of eye. It has been categorized as an Aushadha sadhya vyadhi[3] i.e. curable by medication. In the present study drug Triphaladi compound has shown encouraging clinical outcome in Shushkakshipaka (Dry Eye). Aim: To analyze the pharmacognostical and pharmaceutical evaluation of Triphaladi compound. Materials and method: Final product was subjected to pharmacognostical and physiochemical analysis such as microscopic study loss of drying, ash value, pH etc. Result: Pharmacognostical study showed the presence of contents such as blunted fiber of Daruharidra, prismatic crystal of Yastimadhu, fibers of Punarnava, striated fibers of Gokshura etc. were found on pharmacognostical evaluation. Physico chemical constants like pH, loss on drying, ash value, water soluble extract, HPTLC(High Performance Thin Layer Chromatography) where evaluated along with organoleptic characteristics. Conclusion: The present work was carried out to standardize the finished product of Triphaladi compound in terms of its identity quality and purity. Pharmacognostical and physico chemical observations revealed the specific characters of all active constituents used in the preparation.

Keywords: HPTLC, Pharmacognosy, pharmaceutical, Triphaladi compound, Shushkakshipaka, Dry Eye.