Abstract

CLEANING VALIDATION

Poonam Ingalwad*, Vikram Veer and Ashok Bhosale

Abstract

Validation is art of designing. The purpose of this review is to give information about importance cleaning validation. Cleaning validation that play an important role in preventing risk to patient by assuring that cross-contamination between products is curtailed to acceptable levels. Pharmaceutical substance, excipient, API i.e. active pharmaceutical ingredient may contaminated by other products or APIs, by cleaning agents, microorganisms or by other materials e.g. dust, lubricant, raw material, intermediates. The main purpose of cleaning validation is to improve the effectiveness, prevent cross contamination. The benefits of cleaning validation are compliance with federal regulations, and identification, correction of potential problems.

Keywords: Importance of Cleaning Validation, Cross Contamination & Contamination, Cleaning Validation Guideline, Methodology, Sampling Techniques.