Abstract

REVIEW ON ANTIDIABETIC ACTIVITY OF MEDICINAL PLANTS

Bodkhe Suvarna Pandurang*, Biradar Rutumbara Sangram, Biradar Vinod Rajendra, Muley Sagar Sopanrao

Abstract

Diabetes mellitus is one of the common metabolic disorders affecting a huge number of populations in the world. It is mainly characterized by chronic hyperglycemia, resulting from defects in insulin secretion or insulin action. It is predicted that the number of diabetes patients in the world could reach up to 366 million by the year 2030. Even though the cases of diabetes are increasing day by day, except insulin and oral hypoglycemic drugs no other way of treatment has been successfully developed so far. Thus, the objective of this review is to provide an insight over the pathological and etiological aspects of diabetes. The review also contains brief idea about diabetes mellitus and the list of herbal medicinal plants which shows the antidiabetic activity. Among this list of antidiabetic medicinal plants, five medicinal plants such as syzygium cumini, aloe vera, momordica charantia, azadiracta indica, and annona squamosa are well described. Active chemical constituents, plants parts to be used, and chemical tests for determination of presence of active constituents in the prepared extract are also included in this review. The plants having antidiabetic activity is mainly due to the presence of the secondary metabolites. So, the information provided in this review will helps to the researchers for the development of an alternative methods and medicines rather than insulin and oral hypoglycemic agents for the treatment of diabetes mellitus, which will minimize the complications associated with the diabetes and related disorder.

Keywords: Diabetes mellitus, antidiabetic medicinal plants, chemical tests, animal study.