Abstract

BLOOD TRANSFUSION COMPLICATIONS PREVALENCE PARAMETRIC CAUSES FOR STRESS OF DISEASE AND MANAGEMENT OF TRANSFUSION DEPENDENT THALASSEMIA: A NARRATIVE REVIEW

Happy S. Lulla*, Aishwarya S. Kapure, Snehal L. Lakhani, Dr. Savita D. Patil, Hemakshi Chaudhri and Dr. Vinit M. Warthe

Abstract

Thalassemia are genetically transmitted disorder which is autosomal recessive form by defect of globin chains. This hemoglobinopathy disorder lies from asymptotic to severity to death in uterus of child forming various forms of thalassemia. Prevalence of 3-4% of death annually in India. Thalassemia children suffers many stressful life with disease apart from blood transfusions like Iron Overload, Complications of blood and chelation therapy like Splenomegaly, Hepatomegaly, Growth Retardation, Heart Failure. Better Transfusion therapy assist the severity of complications and standardized care of patient by day care hospitals provides proper transfusion according to guidelines and helps to reduce severity of complications by providing quality of life to patients.

Keywords: Thalassemia, Cooley‘s Anemia, Hemoglobinopathy, Complications of Thalassemia.