Abstract

ANALYSIS OF MICROCRYSTALLINE CELLULOSE AND THEIR PRODUCTS

Ankit Jurla* and Sneha Khadse

Abstract

Microcrystalline cellulose (MCC) has been widely used as an excipient for direct compression due to its good flow ability, compressibility, and compatibility. The analysis of microcrystalline cellulose and their products and Water testing is also performed. Take 90ml SCDM (soyabean casein digest medium) for enrichment of finished product. Add 10gm of sample in SCDM broth, now inoculate 1ml of sample in petri plate and pour soya bean casein agar on the surface of Petri plate then kept it for 15minutes to settle down and after settling incubate it at 37 degree centigrade for 18-48 hours for TAMC (total aerobic microbial count) and 18–72hours for TYMC (total yeast and mould count). Now transfer the 1ml sample in macckonky broth and also 0.1ml in RVSE broth and also streak on the cetrimide agar plate and Mannitol salt agar plate and incubate it for 18 to 24hours and note the result either bacteria are present or absent, it shows the product is good.

Keywords: microcrystalline cellulose powder, cellulose powder, microcrystalline cellulose and carboxy methyl cellulose sodium, silicified microcrystalline cellulose, spirullina powder, S.aureous, E.coli, Salmonella, Pseudomonas.